


Our research is dedicated to the development and optimization of processes for the manufacturing of biopharmaceutical products with mammalian cell lines. We are focused on the development of new tools to improve critical quality attributes of biopharmaceutical products such as glycosylation or protein aggregation. For this purpose we have established various technologies comprising for example the application of cell culture up to the 20 L scale, miRNA technology as well as glycan and protein aggregation analysis. Another important aspect is the development of new process monitoring tools such as soft sensors based on 2D fluorescence spectroscopy. Currently we have started a new research area dealing with digitalization of bioprocesses. In this context we work on new concepts to apply virtual and augmented reality tools in production processes.
Our research group has hosted master and PhD students as well as post-doctoral researchers since 2011. In a number of projects we collaborate with national and international academic institutions and industrial partners. We are always open to new collaborations and projects in the area of innovative process science and production technologies.
Dr. Jakob Birke, Researcher
Dr. Mohammed Milhim, Researcher
Patrick Schlossbauer
Scientific publications
Conference talks
Patents
Entwicklung von M3C-Strategien zur Vermeidung von Produktaggregation in Produktionsprozessen mit Säugerzellen
Verbundprojekt: Proteinaggregation bei der Herstellung moderner Biopharmazeutika
Identifizierung prozessrelevanter miRNAs in Produktionszelllinien